ABSTRACT
@EN The utility of fine needle aspiration (FNA) in the diagnosis of thyroid nodules was assessed in 569 thyroidectomized patients among total 765 cases with thyroid nodules. The available results of FNA biopsy obtained from 430 cases with thyroid
nodules revealed benign lesions in 69.5%, follicular lesions in 21.4% and malignant lesions in 9.1%. The pathological classification of 282 thyroidectomized patients with preoperative FNA results (group 1) was compared to that of 287
thyroidectomized
patients with none of preoperative FNA results (group 2). The group 1 and group 2 showed similar proportion of pathologic classification: malignant nodules were 23.8%, 20.9%, respectively, adenomatous hyperplasia 57.8%, both, and follicular
adenoma
16.3%, 18.8%, respectively. In 67 patients with malignant thyroid diseases, preoperative FNA cytologic diagnosis were malignancy in 28 cases (41.8%), follicular neoplasm in 14 cases, and benign in 25 cases. Sensitivity and specificity of FNA
biopsy
were
52.8% and 97.7%, respectively. The false negative rate of FNA biopsy was 13.0%. In conclusion, although malignant findings in FNA can be helpful information for the treatment of thyroid nodules, further diagnostic tests or surgical consideration
should
not be restricted if FNA showed benign findings (J Kor Soc Endocrinol 8:318~325, 1993).
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